Bimat eye drops contains 0.03%w/v Bimatoprost as its active ingredient. Bimatoprost is primarily used to treat patients with glaucoma by reducing the pressure inside the eyes or the intraocular pressure. The increase in pressure damages the optic nerve fibers leading the gradual loss of sight. Reducing this intraocular pressure reduces the risk of blindness associated with glaucoma. The pressure build-up is caused by a blockage in the drainage system called aqueous humour which is responsible for normal eye pressure. Bimatoprost works by increasing the flow of aqueous humour out of the eyes via spongy tissues called the trabecular network causing a balanced flow of liquid thus reducing eye pressure.
Aside from this, Bimat is also used for the treatment of eyelash hypotrichosis. Eyelash hypotrichosis is a condition where eyelash growth or amount of eyelashes is inadequate. Bimatoprost increases growth of eyelashes, and increases its length, thickness and darkness. This eyelash enhancement effect of Bimatoprost was once observed as a side effect, but is now a desirable effect. Medications such as Bimat are developed with eyelash hypotrichosis as an approved indication. Bimatoprost being a synthetic prostaglandin analog, works by acting on prostaglandin receptors in the hair follicles, stimulating resting follicles to go into their growing follicle phase.
Bimat is manufactured by Ajanta Pharma Ltd.
Bimatoprost for glaucoma:
Before using Bimatoprost, make sure to remove contact lenses and hands are clean. Instill one drop of Bimat to the affected eye, once a day. Hold the eye open, carefully squeeze a drop to the eye, and gently close and reopen eyes to help spread the medication. Continue use of this medication as prescribed by a physician.
Bimat for eyelash hypotrichosis:
Before using Bimat, make sure that the face is clean, hands are clean and contact lenses are removed. Using a sterile applicator, Bimat must be applied at night unless the physician advises otherwise.
Squeeze a drop of Bimat to the tip of the applicator and apply the medication directly at the base of the upper eyelashes, starting from the inner to the outer part of the lash line. Blot excess Bimat solution with a clean tissue or cloth. Eye must not be rinsed off the solution gets into the eye, for it will not cause damage. Note that this medication must not be applied on the lower eyelid to avoid the solution running to the cheeks and other skin areas as it may also cause hair growth to other skin areas.
One applicator must be used for one eyelid only and strictly for one-time use. Throw the applicator after use to avoid contamination. Contact lenses may be reinserted after 15 minutes of drug application.
Results may be visible within 8 to 10 weeks of using Bimat and with a maximum effect by 12 to 16 weeks. Note that there may be a difference in length, thickness, pigmentation, or direction of eyelash growth between the eyes. Eyelashes will return to its original state or appearance in a few weeks or months if the use of this medication is stopped.
This medication must not be used by patients with known hypersensitivity to its active ingredient Bimatoprost and all its inactive ingredients.
This medication is not recommended for use by pregnant and breastfeeding women. Bimat is under Pregnancy Category C, which means animal studies have shown to cause fetal damage, but no evidence has been shown in human studies. It may only be used with the advice of a physician if there are no other safer alternatives and if benefits outweigh risks.
Warnings and Precautions
Inform a healthcare professional of any medical conditions and any medications being taken, to determine if Bimat is safe for use. Caution is advised to patients with the following medical conditions:
- History of glaucoma
- Eye condition called uveitis
- Any infection or swelling in or around the eyes
- History of eye injury or eye surgery
Bimat may interact if combined with other prostaglandin analogs and other eye drops such as:
- Travoprost eyedrops
- Latanoprost eyedrops
- Unoprostone eyedrops
Avoid this solution coming in contact with other skin parts as hair growth may also occur in other skin areas. Make sure the tip of the eye drop bottle must not come in contact with fingers and other things to avoid contamination.
Caution is advised when driving or using heavy machineries. It is best to observe the effect of this medication on one’s eyesight before doing such activities because Bimatoprost may cause vision changes.
Bimat and Alcohol
Bimatoprost (Bimat) does not interact with alcohol and other foods.
It is best to consult a doctor before using Bimat for glaucoma or eyelash hypotrichosis.
Bimat may cause certain side effects but not all patients using this medication will experience this. Common side effects of Bimat are usually mild and safe and don’t require medical attention. These may subside with continued use as the body adjusts to the medication. Side effects include, but not limited to:
- Itchy eyes
- Eye redness
- Eye dryness
- Burning eyes
- Stinging eyes
- Watery eyes
- Increased eye sensitivity to light
- Foreign body sensation
Bimat use may cause a brown pigmentation of the iris and eyelids or change in appearance of the eyes with months or years of use. Pigmentation of the iris is likely permanent but pigmentation of the eyelids is reversible when use of Bimat is discontinued.
Stop using the medication and seek immediate medical attention for any of the following side effects:
- Severe irritation or inflammation of eyes or eyelids
- Red eyelids
- Severe eye pain
- Changes in vision
- Eye infection
Stop using the medication if an allergic reaction occurs, with symptoms of hives, breathing difficulty, swelling of face, lips, tongue or throat. Consult a physician for a complete list of side effects